Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I3RO
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| Former ID |
DNAP001468
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| Drug Name |
Droxidopa
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| Synonyms |
droxidopa; 23651-95-8; L-DOPS; Northera; (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid; threo-Dopaserine; 3916-18-5; DOPS; DL-threo-DOPS; L-Threodops; DL-threo-3,4-Dihydroxyphenylserine; DL-threo-Droxidopa; DL-threo-Dihydroxyphenylserine; UNII-J7A92W69L7; SM 5688; CHEBI:31524; Droxidopa (L-DOPS); threo-beta,3-Dihydroxy-DL-tyrosine; EINECS 223-480-5; beta,3-Dihydroxy-DL-tyrosine threo-; BRN 2852792; L-threo-dihydroxyphenylserine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo-
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| Drug Type |
Small molecular drug
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| Indication | Neurogenic orthostatic hypotension [ICD-11: 8D87.0Y] | Approved | [1], [2], [3] | |
| Company |
Chelsea Therapeutics
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| Structure |
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Download2D MOL |
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| Formula |
C9H11NO5
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| Canonical SMILES |
C1=CC(=C(C=C1C(C(C(=O)O)N)O)O)O
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| InChI |
1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
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| InChIKey |
QXWYKJLNLSIPIN-JGVFFNPUSA-N
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| CAS Number |
CAS 23651-95-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7848340, 10225708, 12013905, 14748940, 15220262, 44423747, 50045941, 50370475, 57335461, 103851036, 104408862, 117541347, 118311826, 126654108, 134995608, 135050567, 137323634, 138163335, 152029318, 160692469, 160824963, 162009751, 162228197, 163092402, 163384817, 163773158, 163883713, 172855924, 175612534, 178103963, 179150202, 196106149, 198948648, 204433783, 210274860, 210280493, 223441551, 226502358, 241076804, 242660130, 249492214, 252348725, 252418289
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| ChEBI ID |
CHEBI:31524
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| ADReCS Drug ID | BADD_D00732 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7391). | |||
| REF 2 | 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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