Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K1NM
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| Former ID |
DNC002719
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| Drug Name |
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
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| Synonyms |
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone; CHEMBL493448; SCHEMBL10247513; CHEMBL1187207; BDBM50252801; DB07342; 1(adamantan1yl) 2(1himidazol1yl) ethanone; 1-(adamantan-1-yl)-2-(imidazol-1-yl)ethanone; 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H20N2O
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| Canonical SMILES |
C1C2CC3CC1CC(C2)(C3)C(=O)CN4C=CN=C4
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| InChI |
1S/C15H20N2O/c18-14(9-17-2-1-16-10-17)15-6-11-3-12(7-15)5-13(4-11)8-15/h1-2,10-13H,3-9H2
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| InChIKey |
BBCQJSMDKDHVKG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Heme oxygenase 1 (HMOX1) | Target Info | Inhibitor | [1] |
| BioCyc | Heme degradation | |||
| KEGG Pathway | Porphyrin and chlorophyll metabolism | |||
| HIF-1 signaling pathway | ||||
| Mineral absorption | ||||
| MicroRNAs in cancer | ||||
| Pathwhiz Pathway | Porphyrin Metabolism | |||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Iron uptake and transport | |||
| WikiPathways | Oxidative Stress | |||
| Transcriptional activation by NRF2 | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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