Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K3LW
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| Former ID |
DAP000895
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| Drug Name |
Malathion
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| Synonyms |
Calmathion; Camathion; Carbafos; Carbetovur; Carbetox; Carbofos; Carbophos; Celthion; Chemathion; Cimexan; Cleensheen; Cythion; Dorthion; Emmatos; Ethiolacar; Etiol; Extermathion; Flair; Forthion; Fosfothion; Fosfotion; Fyfanon; Hilthion; Karbofos; Kypfos; Malacide; Malafor; Malagran; Malakill; Malamar; Malaphele; Malaphos; Malasol; Malaspray; Malataf; Malathiazol; Malathione; Malathiozoo; Malathon; Malathyl; Malation; Malatol; Malatox; Maldison; Malmed; Malphos; Maltox; Mercaptothion; Mercaptotion; Moscarda; Oleophosphothion; Organoderm; Ovide; Paladin; Phosphothion; Prioderm; Sadofos; Sadophos; Sumitox; TAK; Taskil; Vetiol; Zithiol; Carbethoxy malathion; Detm ol ma; Detmol MA; Emmatos extra; Lice Rid;Malathion LV Concentrate; Malathion [USP]; Malation [Polish]; Maltox MLT; Mercaptosuccinic acid diethyl ester; Mercaptotion [Spanish]; Ortho Malathion; Siptox I; Vegfru malatox; AC 26691; EL 4049; Experimental insecticide 4049; Fog 3; Fosfotion 550; Hilthion 25wdp; IFO 13140; Latka 4049; Latka 4049 [Czech]; MET86C_SUPELCO; Malamar 50; Malathion 60; Malathion E50; OMS 1; PS86_SUPELCO; SF 60; Sadofos 30; American cyanamid 4,049; Derbac-M; ENT 17,034; Four thousand forty-nine; Insecticide no. 4049; Kop-Thionkypfosmalacide; Kop-thion; Malathion (USP); Malathion (old ID); Ovide (TN); Staeubol-Puder; Suleo-M; TM-4049; Kill-A-Mite; MALATHION, 96%; Malathion-2,3-14C; 8059HC
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| Drug Type |
Small molecular drug
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| Indication | Pediculus capitis infestation [ICD-11: 1G00.0; ICD-10: B85.0; ICD-9: 132] | Approved | [1] | |
| Therapeutic Class |
Parasympathomimetics
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| Structure |
 |
Download2D MOL |
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| Formula |
C10H19O6PS2
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| Canonical SMILES |
CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
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| InChI |
1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3
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| InChIKey |
JXSJBGJIGXNWCI-UHFFFAOYSA-N
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| CAS Number |
CAS 121-75-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9700, 72491, 5635026, 7847600, 8152511, 10505736, 11341657, 11361840, 11364699, 11367261, 11369823, 11371904, 11374164, 11377987, 11484812, 11487242, 11489044, 11490629, 11492468, 11495609, 11533337, 14895285, 17389839, 24862222, 24896587, 24897403, 24899302, 26680255, 26753130, 26753131, 29223115, 46505287, 47885548, 47959913, 48413955, 48415164, 48421591, 48423623, 48425254, 48425934, 49854841, 50105655, 50105656, 50105657, 53790330, 56312213, 56314278, 56369337, 57322090, 57649475
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| ChEBI ID |
CHEBI:6651
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| ADReCS Drug ID | BADD_D01346 | |||
| SuperDrug ATC ID |
P03AX03
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| SuperDrug CAS ID |
cas=000121755
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 078743. | |||
| REF 2 | Acetylcholinesterase activity in Corbicula fluminea Mull., as a biomarker of organophosphate pesticide pollution in Pinacanauan River, Philippines. Environ Monit Assess. 2010 Jun;165(1-4):331-40. | |||
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