Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P5CD
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| Former ID |
DIB010247
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| Drug Name |
Iocetamic acid
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| Synonyms |
IOCETAMIC ACID; Cholebrine; Colebrina; Cholimil; Acidum jocetamicum; 16034-77-8; Acide iocetamique [INN-French]; Acidum iocetamicum [INN-Latin]; Acido iocetamico [INN-Spanish]; HSDB 3344; DRC 1201; EINECS 240-173-1; MP-620; MP 620; BRN 2171366; N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-beta-alanine; N-Acetyl-N-(3-amino-2,4,6-triiodophenl)-2-methyl-beta-alanine; beta-Alanine, N-acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-; Propanoic acid, 3-(acetyl(3-amino-2,4,6-triiodophenyl)amino)-2-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Bladder disease [ICD-11: DC11-DC1Z; ICD-10: K80-K87] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H13I3N2O3
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| Canonical SMILES |
CC(CN(C1=C(C=C(C(=C1I)N)I)I)C(=O)C)C(=O)O
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| InChI |
1S/C12H13I3N2O3/c1-5(12(19)20)4-17(6(2)18)11-8(14)3-7(13)10(16)9(11)15/h3,5H,4,16H2,1-2H3,(H,19,20)
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| InChIKey |
GSVQIUGOUKJHRC-UHFFFAOYSA-N
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| CAS Number |
CAS 16034-77-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:91662
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| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Abundace of Studied Microbe(s) Regulated by Drug | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Lactobacillales | ||||
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Studied Microbe: Lactobacillus paracasei
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[2] | |||
| Hierarchy | ||||
| Abundance Change | Decrease | |||
| Experiment Method | High-throughput screening | |||
| Description | The abundance of Lactobacillus paracasei was decreased by Iocetamic acid (adjusted p-values: 2.86E-05). | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Extensive impact of non-antibiotic drugs on human gut bacteria. Nature. 2018 Mar 29;555(7698):623-628. | |||
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