Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T5MO
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| Former ID |
DNC002540
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| Drug Name |
5alpha-Androstan-3,17-Dione
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| Synonyms |
Androstanedione; 5alpha-Androstane-3,17-dione; 846-46-8; 5alpha-Androstan-3,17-dione; 5a-Androstanedione; 5-alpha-Androstane-3,17-dione; Dihydroandrostendione; 5alpha-Androstanedione; UNII-2KR72RNR8Z; Androstane-3,17-dione; 5.alpha.-Androstanedione; dihydroandrostenedione; 5a-Androstane-3,17-dione; 2KR72RNR8Z; A-androstane-3,17-dione; CHEMBL1230438; CHEBI:15994; 5.alpha.-Androsta-3,17-dione; RAJWOBJTTGJROA-WZNAKSSCSA-N; Androstane-3,17-dione, (5alpha)-; 5.alpha.-Androstane-3,17-dione; Androstane-3, (5.alpha.)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H28O2
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| Canonical SMILES |
CC12CCC(=O)CC1CCC3C2CCC4(C3CCC4=O)C
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| InChI |
1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12-,14-,15-,16-,18-,19-/m0/s1
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| InChIKey |
RAJWOBJTTGJROA-WZNAKSSCSA-N
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| CAS Number |
CAS 846-46-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2382, 3943, 75251, 108764, 831357, 841384, 854748, 7885430, 8145054, 9377310, 12161429, 15492483, 25621459, 30426054, 46505490, 46508701, 50897570, 57400000, 85300779, 92298501, 103935286, 104246631, 113476485, 126523661, 126722984, 129100947, 135034420, 137016148, 139692791, 152095020, 160964805, 162921172, 164835841, 172847800, 179322734, 198976101, 224517174, 227137944, 241148567, 250112785
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| ChEBI ID |
CHEBI:15994
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1) | Target Info | Inhibitor | [1] |
| Hydroxysteroid dehydrogenase 3-beta (HSD3B) | Target Info | Inhibitor | [1] | |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Estradiol biosynthesis I | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | The canonical retinoid cycle in rods (twilight vision) | |||
| WikiPathways | Steroid Biosynthesis | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Prostate Cancer | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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