Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TP5H
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| Drug Name |
Esketamine
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| Synonyms |
(S)-Ketamine; l-Ketamine; (S)-(-)-Ketamine; 33643-46-8; S-Ketamine; UNII-50LFG02TXD; 50LFG02TXD; (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone; CHEBI:60799; esketamine HCl; (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone; cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (2S)-; 6740-88-1 (Parent); Esketamine [USAN:INN:BAN]; S-Ketamin; S-(-)-Ketamine; Esketamine (USAN/INN); AC1L4AD8; DSSTox_CID_27787; DSSTox_RID_82562; DSSTox_GSID_47810; SCHEMBL5512024; GTPL9152; CHEMBL395091; DTXSID6047810; YQEZ
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| Indication | Depression [ICD-11: 6A70-6A7Z; ICD-9: 311] | Phase 3 | [1] | |
| Company |
Janssen Research & Development Raritan, NJ
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H16ClNO
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| Canonical SMILES |
CNC1(CCCCC1=O)C2=CC=CC=C2Cl
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| InChI |
1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1
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| InChIKey |
YQEZLKZALYSWHR-ZDUSSCGKSA-N
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| CAS Number |
CAS 33643-46-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:60799
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| ADReCS Drug ID | BADD_D02488 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Antagonist | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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