Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W6ZF
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| Former ID |
DAP000694
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| Drug Name |
Sevoflurane
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| Synonyms |
Sevofluran; Sevoflurano; Sevofluranum; Sevofrane; Sevorane; Sojourn; Ultane; Fluoromethyl hexafluoroisopropyl ether; Bax 3084; F0691; MR6S4; MR_6S4; PC4681; Sevoflurano [INN-Spanish]; Sevofluranum [INN-Latin]; Ultane (TN); Sevoflurane (JAN/USAN/INN); Sevoflurane [USAN:INN:BAN:JAN]; Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether; Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether; Fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether; 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
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| Company |
Abbott Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C4H3F7O
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| Canonical SMILES |
C(OC(C(F)(F)F)C(F)(F)F)F
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| InChI |
1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
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| InChIKey |
DFEYYRMXOJXZRJ-UHFFFAOYSA-N
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| CAS Number |
CAS 28523-86-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9723, 3215276, 6493020, 7847613, 7980594, 8153199, 12012762, 12075314, 15120951, 29224263, 46508591, 49968899, 50112674, 50769024, 57322653, 81065570, 85305373, 87560819, 92714283, 95693806, 99452954, 103770677, 104308565, 121362326, 125368119, 126624262, 126655524, 127726271, 131308872, 131465785, 134213127, 134337983, 134997737, 135589757, 137005407, 142416197, 143461391, 144076360, 144205978, 160810390, 160964568, 162177516, 162829968, 164791075, 174528671, 175268320, 175611312, 176247785, 178103869, 179116892
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| ChEBI ID |
CHEBI:9130
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| ADReCS Drug ID | BADD_D02015 | |||
| SuperDrug ATC ID |
N01AB08
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| SuperDrug CAS ID |
cas=028523866
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Antagonist | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7296). | |||
| REF 2 | Anaesthetic drugs: linking molecular actions to clinical effects. Curr Pharm Des. 2006;12(28):3665-79. | |||
| REF 3 | Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats. Can J Anaesth. 2009 Feb;56(2):126-35. | |||
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