Drug Information
Drug General Information | Top | |||
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Drug ID |
D00AJB
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Former ID |
DNC014492
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Drug Name |
Voacangine
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Synonyms |
Voacangine; CHEMBL182120; Carbomethoxyibogaine; (-)-Voacangine; 510-22-5; methyl ethyl(methoxy)[ ]carboxylate; AC1L2JJV; 12-Methoxyibogamine-18-carboxylic acid methyl ester; MMAYTCMMKJYIAM-RUGRQLENSA-N; BDBM50329104; ZINC100392804; Methyl (1S)-3,13-diaza-17-ethyl-7-methoxypentacyclo[13.3.1.0< 2,10> 4,9> 13,18> ]nonadeca-2(10),4,6,8-tetraenecarboxylate
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C22H28N2O3
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Canonical SMILES |
CCC1CC2CC3(C1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC)C(=O)OC
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InChI |
1S/C22H28N2O3/c1-4-14-9-13-11-22(21(25)27-3)19-16(7-8-24(12-13)20(14)22)17-10-15(26-2)5-6-18(17)23-19/h5-6,10,13-14,20,23H,4,7-9,11-12H2,1-3H3/t13-,14-,20-,22+/m0/s1
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InChIKey |
MMAYTCMMKJYIAM-RUGRQLENSA-N
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CAS Number |
CAS 510-22-5
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:141966
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Target and Pathway | Top | |||
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Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
KEGG Pathway | Glycerophospholipid metabolism | |||
Cholinergic synapse | ||||
Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
Nicotinic acetylcholine receptor signaling pathway | ||||
Pathwhiz Pathway | Phospholipid Biosynthesis | |||
Pathway Interaction Database | ATF-2 transcription factor network | |||
WikiPathways | Monoamine Transport | |||
Biogenic Amine Synthesis | ||||
Acetylcholine Synthesis | ||||
Integrated Pancreatic Cancer Pathway |
References | Top | |||
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REF 1 | Indole alkaloids from Ervatamia hainanensis with potent acetylcholinesterase inhibition activities. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6185-7. |
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