Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00ICM
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| Former ID |
DIB006630
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| Drug Name |
Naltiazem hydrochloride
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| Synonyms |
Ro-23-6152; Ro-23-6152/001; (+)-cis-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-2,3,4,5-tetrahydronaphtho[1,2-b][1,4]thiazepin-4-one hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C26H29ClN2O4S
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| Canonical SMILES |
CC(=O)OC1C(SC2=C(C=CC3=CC=CC=C32)N(C1=O)CCN(C)C)C4=CC=C(C=C4)OC.Cl
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| InChI |
1S/C26H28N2O4S.ClH/c1-17(29)32-23-24(19-9-12-20(31-4)13-10-19)33-25-21-8-6-5-7-18(21)11-14-22(25)28(26(23)30)16-15-27(2)3;/h5-14,23-24H,15-16H2,1-4H3;1H/t23-,24+;/m1./s1
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| InChIKey |
SFTBZKFGODNAKF-ITNPDYSASA-N
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| CAS Number |
CAS 108383-96-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Blocker | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000300) | |||
| REF 2 | Assessment of hyperglycemia after calcium channel blocker overdoses involving diltiazem or verapamil. Crit Care Med. 2007 Sep;35(9):2071-5. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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