Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00IUB
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| Former ID |
DNC008511
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| Drug Name |
4-CYANOPHENOL
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| Synonyms |
4-Hydroxybenzonitrile; 4-Cyanophenol; 767-00-0; p-Hydroxybenzonitrile; P-CYANOPHENOL; Benzonitrile, 4-hydroxy-; Benzonitrile, p-hydroxy-; 4-CYANO PHENOL; 4-Hydroxybenzoic acid nitrile; 4-hydroxy-benzonitrile; 4-Hydroxy benzonitrile; 4-hydroxybenzenecarbonitrile; UNII-1S13529YJU; EINECS 212-175-2; C7H5NO; NSC 400524; AI3-52392; CHEBI:38622; CVNOWLNNPYYEOH-UHFFFAOYSA-N; 1S13529YJU; 4-Cyanophenol, 99%; paracyanophenol; p-cyano-phenol; 4-cyano-phenol; 4 -cyanophenol; para-cyanophenol;; 4-hydroxybezonitrile; p-hydroxybenzo-nitrile
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H5NO
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| Canonical SMILES |
C1=CC(=CC=C1C#N)O
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| InChI |
1S/C7H5NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H
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| InChIKey |
CVNOWLNNPYYEOH-UHFFFAOYSA-N
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| CAS Number |
CAS 767-00-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:38622
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase VI (CA-VI) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase XII (CA-XII) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| IL4 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | ||||
| Reactome | Reversible hydration of carbon dioxide | |||
| Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid. Bioorg Med Chem. 2008 Aug 1;16(15):7424-8. | |||
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