Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00KFB
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| Drug Name |
Dextromethorphan Polistirex
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| Indication | Dry cough [ICD-11: MD12; ICD-10: R05] | Approved | [1] | |
| Company |
Reckitt Benckiser Llc
|
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| Structure |
 |
Download2D MOL
|
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| Formula |
C18H26BrNO
|
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| Canonical SMILES |
CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br
|
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| InChI |
1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1
|
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| InChIKey |
MISZALMBODQYFT-URVXVIKDSA-N
|
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| CAS Number |
CAS 125-69-9
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor sigma 1 (OPRS1) | Target Info | Modulator | [2] |
| Serotonin transporter (SERT) | Target Info | Modulator | [2] | |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
| 5HT2 type receptor mediated signaling pathway | ||||
| 5HT3 type receptor mediated signaling pathway | ||||
| 5HT4 type receptor mediated signaling pathway | ||||
| WikiPathways | Monoamine Transport | |||
| SIDS Susceptibility Pathways | ||||
| NRF2 pathway | ||||
| Synaptic Vesicle Pathway | ||||
| Serotonin Transporter Activity | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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