Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00PSJ
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| Former ID |
DNC011648
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| Drug Name |
2-(3-Methyl-3H-imidazol-4-yl)-ethylamine
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| Synonyms |
3-Methylhistamine; Tau-methylhistamine; 644-42-8; Imidazole, 5-(2-aminoethyl)-1-methyl-; L-histamine deriv. 1; 2-(1-methyl-1H-imidazol-5-yl)ethan-1-amine; 1H-Imidazole-5-ethanamine, 1-methyl-; CHEMBL14722; 2-(1-methyl-1H-imidazol-5-yl)ethanamine; CPAGZVLINCPJEH-UHFFFAOYSA-N; 2-(3-methylimidazol-4-yl)ethanamine; 3-Methyl Histamine Dihydrochloride; (r)-a-methylhistamine; AC1Q4WNL; SCHEMBL946729; BDBM7967; AC1L2C25; CTK5C1256; DTXSID10214651; ZINC403074; AKOS006340201; 1H-Imidazole-5-ethanamine,1-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C6H11N3
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| Canonical SMILES |
CN1C=NC=C1CCN
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| InChI |
1S/C6H11N3/c1-9-5-8-4-6(9)2-3-7/h4-5H,2-3,7H2,1H3
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| InChIKey |
CPAGZVLINCPJEH-UHFFFAOYSA-N
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| CAS Number |
CAS 644-42-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine. Bioorg Med Chem Lett. 1998 May 19;8(10):1133-8. | |||
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