Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00QCL
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| Former ID |
DNC012026
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| Drug Name |
SOPHOFLAVESCENOL
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| Synonyms |
SOPHOFLAVESCENOL; 216450-65-6; CHEMBL77651; SCHEMBL14563970; MolPort-039-339-033; ZINC4199939; HY-N2284; BCP24815; LMPK12112538; BDBM50116711; AKOS032945037; CS-6033; 3,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-4H-chromen-4-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H20O6
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| Canonical SMILES |
CC(=CCC1=C2C(=C(C=C1O)OC)C(=O)C(=C(O2)C3=CC=C(C=C3)O)O)C
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| InChI |
1S/C21H20O6/c1-11(2)4-9-14-15(23)10-16(26-3)17-18(24)19(25)20(27-21(14)17)12-5-7-13(22)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
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| InChIKey |
VMLJAWUWVVHRNG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 4A (PDE4A) | Target Info | Inhibitor | [1] | |
| Phosphodiesterase 4B (PDE4B) | Target Info | Inhibitor | [1] | |
| Phosphodiesterase 5A (PDE5A) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Purine metabolism | |||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | ||||
| Reactome | DARPP-32 events | |||
| G alpha (s) signalling events | ||||
| cGMP effects | ||||
| WikiPathways | G Protein Signaling Pathways | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| Myometrial Relaxation and Contraction Pathways | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2313-6. | |||
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