Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00QLM
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| Former ID |
DIB018237
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| Drug Name |
[3H]alphabeta-meATP
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| Synonyms |
Diphosphomethylphosphonic acid adenosyl ester; alpha,beta-Methylene ATP; alpha,beta-meATP; 7292-42-4; UNII-NYX13NT29D; diphosphomethylphosphonic acid adenosyl ester; alpha,beta-Methyleneadenosine 5'-triphosphate; EINECS 230-723-9; NYX13NT29D; ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE; CHEMBL132722; CHEBI:35056; 5'-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl)adenosine; 5'-(Hydrogen((hydroxy(phosphonooxy)phosphinyl)methyl)phosphonate)adenosine; adenosine 5'-[alpha,beta-methylene]triphosphate; AMP-CPP; Adenosine 5'-(hydrogen; Alpha,Beta-Methyleneadenosine-5'-Triphosphate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H18N5O12P3
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| Canonical SMILES |
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(CP(=O)(O)OP(=O)(O)O)O)O)O)N
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| InChI |
1S/C11H18N5O12P3/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25)/t5-,7-,8-,11-/m1/s1
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| InChIKey |
CAWZRIXWFRFUQB-IOSLPCCCSA-N
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| CAS Number |
CAS 7292-42-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:35056
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenylate cyclase (ADCY) | Target Info | Inhibitor | [3] |
| Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase (Bact folK) | Target Info | Inhibitor | [3] | |
| Bacterial NH(3)-dependent NAD(+) synthetase (Bact nadE) | Target Info | Inhibitor | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5405). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4093). | |||
| REF 3 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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