Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00RUN
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| Former ID |
DNC011643
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| Drug Name |
4-(7,7-Dimethyl-oct-3-ynyl)-1H-imidazole
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| Synonyms |
CHEMBL280076; 4-(7,7-Dimethyl-oct-3-ynyl)-1H-imidazole; 1H-Imidazole, 5-(7,7-dimethyl-3-octyn-1-yl)-; SCHEMBL7619037; PDSP1_000108; BDBM50070214; PDSP2_000108; GT 2293; 209599-16-6
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H20N2
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| Canonical SMILES |
CC(C)(C)CCC#CCCC1=CN=CN1
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| InChI |
1S/C13H20N2/c1-13(2,3)9-7-5-4-6-8-12-10-14-11-15-12/h10-11H,6-9H2,1-3H3,(H,14,15)
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| InChIKey |
CNQBABLURIQXNU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine. Bioorg Med Chem Lett. 1998 May 19;8(10):1133-8. | |||
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