Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00UYE
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| Former ID |
DAP000230
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| Drug Name |
Meperidine
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| Synonyms |
Demarol; Demerol; Dolcontral; Dolosal; Dolsin; Isonipecain; Isonipecaine; Lidol; Lydol; Meperidol; Nemerol; Pethanol; Pethidin; Pethidine; Pethidineter; Pethidinum; Petidina; Petydyna; Phetidine; Piperosal; Pipersal; Meperidine solution; Methyl phenylpiperidine carbonic acid ethyl ester; Operidine EPJ I; Pethidine DBL; Petydyna [Polish]; Demerol (TN); Operidine EPJ-I; Pethidine (INN); Pethidine DBL (TN); Pethidinum [INN-Latin]; Petidina [INN-Spanish]; Ethyl 1-methyl-4-phenylisonipecotate; Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate; N-Methyl-4-phenyl-4-carbethoxypiperidine; Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester; YIsonipecotic acid, 1-methyl-4-phenyl-, ethyl ester (8CI); 1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester [German]; 1-Methyl-4-phenylisonipecotic acid, ethyl ester;1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester; 4-Carbethoxy-1-methyl-4-phenylpiperidine; 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Approved | [1] | |
| Therapeutic Class |
Anesthetics
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| Company |
Apotex Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H21NO2
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| Canonical SMILES |
CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
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| InChI |
1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3
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| InChIKey |
XADCESSVHJOZHK-UHFFFAOYSA-N
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| CAS Number |
CAS 57-42-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9338, 841258, 4359668, 7978480, 8152545, 10527888, 11336158, 11361397, 11462369, 14823367, 24882043, 29223169, 46506899, 47736577, 48416212, 49986147, 50185474, 53789706, 57322120, 57651808, 85209612, 96025030, 103184537, 103936336, 104305308, 126407782, 129659418, 134337544, 134970866, 137003750, 140053016, 160963800, 175267872, 177513108, 178103795, 179148680, 184546706, 223440287, 224511988, 226413511, 241102133, 249933926
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| ChEBI ID |
CHEBI:6754
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| ADReCS Drug ID | BADD_D01384 ; BADD_D01385 | |||
| SuperDrug ATC ID |
N02AB02
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| SuperDrug CAS ID |
cas=000057421
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor Alpha-2 (ADRA2) | Target Info | Agonist | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Meperidine, remifentanil and tramadol but not sufentanil interact with alpha(2)-adrenoceptors in alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor ... Eur J Pharmacol. 2008 Mar 17;582(1-3):70-7. | |||
| REF 3 | Meperidine exerts agonist activity at the alpha(2B)-adrenoceptor subtype. Anesthesiology. 2002 Jun;96(6):1420-6. | |||
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