Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00WON
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| Former ID |
DNC011568
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| Drug Name |
3-Ethyl-3-methyl-dihydro-furan-2-one
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| Synonyms |
alpha-Emgbl; 2-Ethyl-2-methyl-4-butyrolactone; 3-ethyl-3-methyldihydrofuran-2(3h)-one; 31004-76-9; AC1Q6HQE; CHEBI:35057; 2(3H)-Furanone, 3-ethyldihydro-3-methyl-; alpha-Ethyl-alpha-methyl-gamma-butyrolactone; SureCN132980; C13714; AC1L53DL; SCHEMBL132980; CHEMBL285171; 3-ethyl-3-methyloxolan-2-one; CTK4G6275; 3-ethyl-3-methyl-tetrahydrofuran-2-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H12O2
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| Canonical SMILES |
CCC1(CCOC1=O)C
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| InChI |
1S/C7H12O2/c1-3-7(2)4-5-9-6(7)8/h3-5H2,1-2H3
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| InChIKey |
DRTXQTMTWPIHLI-UHFFFAOYSA-N
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| CAS Number |
CAS 31004-76-9
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:35057
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| Serotonergic synapse | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant ... J Med Chem. 1994 Jan 21;37(2):275-86. | |||
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