Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00XUE
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| Former ID |
DNC012969
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| Drug Name |
(S)-2-amino-3-cyclohexylpropanoic acid
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| Synonyms |
27527-05-5; (S)-2-amino-3-cyclohexylpropanoic acid; L-Cyclohexylalanine; H-Cha-OH; (2S)-2-amino-3-cyclohexylpropanoic acid; 3-Cyclohexyl-L-alanine; L-3-Cyclohexylalanine; (S)-2-Amino-3-cyclohexylpropionic acid; BETA-CYCLOHEXYL-ALANINE; L-beta-Cyclohexylalanine; UNII-GYR4SF0FVQ; GYR4SF0FVQ; CHEMBL383208; Cyclohexanepropanoic acid, alpha-amino-, (alphaS)-; 2-AMINO-3-CYCLOHEXYL-PROPIONIC ACID; 3-cyclohexylalanine; b-cyclohexyl alanine; beta-cyclohexylalanine; PubChem5760; beta-cyclohexyl alanine; AC1LEHTM; AC1Q5QKA
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H17NO2
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| Canonical SMILES |
C1CCC(CC1)CC(C(=O)O)N
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| InChI |
1S/C9H17NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h7-8H,1-6,10H2,(H,11,12)/t8-/m0/s1
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| InChIKey |
ORQXBVXKBGUSBA-QMMMGPOBSA-N
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| CAS Number |
CAS 27527-05-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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