Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00ZWG
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| Former ID |
DIB008844
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| Drug Name |
NS-638
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| Synonyms |
150493-34-8; NS-638; NS638; 2-Amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole; 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine; 1H-Benzimidazol-2-amine,1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)-; NS 638; GXQCVUZORDAARJ-UHFFFAOYSA-N; ACMC-20n5zm; AC1L2SIQ; SCHEMBL3083259; ZINC5752; CTK4C6667; DTXSID10164561; MolPort-046-033-572; BCP20747; AKOS032947353; 1-((4-Chlorophenyl)methyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine; CS-6337; KB-227320; HY-101428
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| Drug Type |
Small molecular drug
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
NeuroSearch A/S
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H11ClF3N3
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| Canonical SMILES |
C1=CC(=CC=C1CN2C3=C(C=C(C=C3)C(F)(F)F)N=C2N)Cl
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| InChI |
1S/C15H11ClF3N3/c16-11-4-1-9(2-5-11)8-22-13-6-3-10(15(17,18)19)7-12(13)21-14(22)20/h1-7H,8H2,(H2,20,21)
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| InChIKey |
GXQCVUZORDAARJ-UHFFFAOYSA-N
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| CAS Number |
CAS 150493-34-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005354) | |||
| REF 2 | Pharmacological profile and anti-ischemic properties of the Ca(2+)-channel blocker NS-638. Neurol Res. 1995 Oct;17(5):353-60. | |||
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