Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01AGR
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| Former ID |
DNC008885
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| Drug Name |
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
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| Synonyms |
CHEMBL521211; 1-[5-(4-Chlorophenyl)-2-furoyl]piperazine; BDBM50270649
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H15ClN2O2
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| Canonical SMILES |
C1CN(CCN1)C(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl
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| InChI |
1S/C15H15ClN2O2/c16-12-3-1-11(2-4-12)13-5-6-14(20-13)15(19)18-9-7-17-8-10-18/h1-6,17H,7-10H2
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| InChIKey |
FSVUGYFGMKVKHY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.5 (SCN5A) | Target Info | Inhibitor | [1] |
| Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Cardiac Progenitor Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. | |||
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