Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01BJZ
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| Former ID |
DNC004944
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| Drug Name |
SNAP-5036
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| Synonyms |
SNAP-5036; CHEMBL282214; SCHEMBL7034334; NJWKVUCAVMYELV-UHFFFAOYSA-N; BDBM50160147; 2-[(4-Methoxyphenethyl)aminomethyl]-1,2,3,4-tetrahydronaphthalene; 2- [(4-Methoxyphenethyl)aminomethyl]-1,2,3,4-tetrahydronaphthalene
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H25NO
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| Canonical SMILES |
COC1=CC=C(C=C1)CCNCC2CCC3=CC=CC=C3C2
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| InChI |
1S/C20H25NO/c1-22-20-10-7-16(8-11-20)12-13-21-15-17-6-9-18-4-2-3-5-19(18)14-17/h2-5,7-8,10-11,17,21H,6,9,12-15H2,1H3
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| InChIKey |
NJWKVUCAVMYELV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| AMPK signaling pathway | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Vascular smooth muscle contraction | ||||
| Salivary secretion | ||||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Reactome | Adrenoceptors | |||
| G alpha (q) signalling events | ||||
| G alpha (12/13) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Endothelin Pathways | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| AMPK Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacophore identification of alpha(1A)-adrenoceptor antagonists. Bioorg Med Chem Lett. 2005 Feb 1;15(3):657-64. | |||
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