Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01CAC
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| Former ID |
DNC009867
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| Drug Name |
(4-methoxyphenyl)(4-phenylazepan-1-yl)methanone
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| Synonyms |
CHEMBL562195; (4-methoxyphenyl)(4-phenylazepan-1-yl)methanone; SCHEMBL19248204
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H23NO2
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| Canonical SMILES |
COC1=CC=C(C=C1)C(=O)N2CCCC(CC2)C3=CC=CC=C3
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| InChI |
1S/C20H23NO2/c1-23-19-11-9-18(10-12-19)20(22)21-14-5-8-17(13-15-21)16-6-3-2-4-7-16/h2-4,6-7,9-12,17H,5,8,13-15H2,1H3
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| InChIKey |
SLZXHOMMTNEABC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4563-5. | |||
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