Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01DTQ
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| Former ID |
DIB017013
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| Drug Name |
PXS-2076
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| Synonyms |
PXS-2000; PXS-2030; Cannabinoid CB2 agonist (rheumatoid arthritis), Pharmaxis; TNFrelease inhibitor (rheumatoid arthritis), Pharmaxis
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Terminated | [1] | |
| Company |
Pharmaxis Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021746) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57). | |||
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