Drug Information
Drug General Information | Top | |||
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Drug ID |
D01FRK
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Former ID |
DIB002949
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Drug Name |
LA-N8
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Synonyms |
GlycoPEG-FVIII; Long-acting recombinant FVIIII (N8), Novo Nordisk; Factor VIII (recombinant/GlycoPEGylated, hemophilia A), Novo Nordisk/Neose
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Indication | Factor VIII deficiency [ICD-11: 3B10; ICD-10: D66] | Investigative | [1] | |
Company |
Neose Technologies Inc
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Target and Pathway | Top | |||
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Target(s) | Coagulation factor VIII (F8) | Target Info | Modulator | [1] |
KEGG Pathway | Complement and coagulation cascades | |||
Panther Pathway | Blood coagulation | |||
Pathwhiz Pathway | Coagulation | |||
Reactome | Platelet degranulation | |||
Intrinsic Pathway of Fibrin Clot Formation | ||||
Common Pathway of Fibrin Clot Formation | ||||
COPII (Coat Protein 2) Mediated Vesicle Transport | ||||
Cargo concentration in the ER | ||||
WikiPathways | Complement and Coagulation Cascades | |||
Blood Clotting Cascade | ||||
Formation of Fibrin Clot (Clotting Cascade) |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2607). |
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