Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01IUI
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| Former ID |
DNC005286
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| Drug Name |
JWH-253
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| Synonyms |
JWH-253; UNII-E28U9TD6JM; E28U9TD6JM; CHEMBL188887; 2-(3-methoxyphenyl)-1-(2-methyl-1-pentyl-1H-indol-3-yl)ethanone; BDBM50170334; Ethanone, 2-(3-methoxyphenyl)-1-(2-methyl-1-pentyl-1H-indol-3-yl)-; 2-(3-Methoxy-phenyl)-1-(2-methyl-1-pentyl-1H-indol-3-yl)-ethanone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C23H27NO2
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| Canonical SMILES |
CCCCCN1C(=C(C2=CC=CC=C21)C(=O)CC3=CC(=CC=C3)OC)C
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| InChI |
1S/C23H27NO2/c1-4-5-8-14-24-17(2)23(20-12-6-7-13-21(20)24)22(25)16-18-10-9-11-19(15-18)26-3/h6-7,9-13,15H,4-5,8,14,16H2,1-3H3
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| InChIKey |
QZLRCHSRCYFMFK-UHFFFAOYSA-N
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| CAS Number |
CAS 864445-46-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4110-3. | |||
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