Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01IWD
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| Former ID |
DNC004414
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| Drug Name |
MDL-74156
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| Synonyms |
Mdl 74156; Hydrodolasetron; Mdl-74156; 127951-99-9; 1H-Indole-3-carboxylicacid, octahydro-3-hydroxy-2,6-methano-2H-quinolizin-8-yl ester; 1-H-Indole-3-carboxylic acid, trans-octahydro-3-hydroxy-2,6-methano-2H-quinolizin-8-yl ester; ACMC-20msnw; AC1L4LYC; CHEMBL498572; SCHEMBL7281981; AC1Q60Y9; CTK4B5810; 1H-Indole-3-carboxylic acid, octahydro-3-hydroxy-2,6-methano-2H-quinolizin-8-yl ester; BDBM50412171; AKOS030254922; 10-hydroxy-8-azatricyclo[5.3.1.03,8]undec-5-yl 1h-indole-3-carboxylate; LS-172694; J-005559
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H22N2O3
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| Canonical SMILES |
C1C2CC3CC(CC1N3CC2O)OC(=O)C4=CNC5=CC=CC=C54
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| InChI |
1S/C19H22N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,18,20,22H,5-8,10H2
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| InChIKey |
MLWGAEVSWJXOQJ-UHFFFAOYSA-N
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| CAS Number |
CAS 127951-99-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Inhibitor | [1] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Potassium Channels | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2773-5. | |||
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