Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01KNY
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| Former ID |
DIB015254
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| Drug Name |
LCB-2183
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Phase 2 | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H10N4O2
|
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| Canonical SMILES |
CCOCC1=NC2=NC=CN=C2C(=O)N1
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| InChI |
1S/C9H10N4O2/c1-2-15-5-6-12-8-7(9(14)13-6)10-3-4-11-8/h3-4H,2,5H2,1H3,(H,11,12,13,14)
|
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| InChIKey |
SFWVULIFVPNTOF-UHFFFAOYSA-N
|
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| CAS Number |
CAS 133914-85-9
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine receptor (HR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | LCB 2183 inhibits tracheal hyperreactivity and pulmonary inflammation in mouse airways. Eur J Pharmacol. 1995 Aug 25;282(1-3):103-9. | |||
| REF 2 | LCB 2183 inhibits the inflammation associated with oxazolone-induced contact sensitivity. Int J Immunopharmacol. 1994 Aug;16(8):675-83. | |||
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