Drug Information
Drug General Information | Top | |||
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Drug ID |
D01MPK
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Former ID |
DNC004506
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Drug Name |
3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione
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Synonyms |
CHEMBL357775; 2,5-Pyrrolidinedione, 3-(4-aminophenyl)-1-methyl-; 59512-13-9; 3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione; CTK1E7233; DTXSID50490593; BDBM50025151; AKOS022647888
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H12N2O2
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Canonical SMILES |
CN1C(=O)CC(C1=O)C2=CC=C(C=C2)N
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InChI |
1S/C11H12N2O2/c1-13-10(14)6-9(11(13)15)7-2-4-8(12)5-3-7/h2-5,9H,6,12H2,1H3
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InChIKey |
QMQMEAAIWVAXHW-UHFFFAOYSA-N
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CAS Number |
CAS 59512-13-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Estradiol biosynthesis II | ||||
Estradiol biosynthesis I | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
NetPath Pathway | FSH Signaling Pathway | |||
Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Reactome | Endogenous sterols | |||
WikiPathways | Metapathway biotransformation | |||
Tryptophan metabolism | ||||
Oxidation by Cytochrome P450 | ||||
Ovarian Infertility Genes | ||||
Metabolism of steroid hormones and vitamin D | ||||
FSH signaling pathway | ||||
Integrated Breast Cancer Pathway | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione. J Med Chem. 1986 Apr;29(4):520-3. |
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