Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01MVX
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| Former ID |
DNC002660
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| Drug Name |
TACRINE(8)-4-AMINOQUINOLINE
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| Synonyms |
TACRINE(8)-4-AMINOQUINOLINE; CHEMBL1082738; A8B; N-quinolin-4-yl-N'-(1,2,3,4-tetrahydroacridin-9-yl)octane-1,8-diamine; AC1LCVTY; BDBM9441; SCHEMBL20553457; DB04616; Heterodimeric Tacrine-Based Inhibitor 8g; N-(1,2,3,4-Tetrahydroacridine-9-yl)-N'-(4-quinolyl)-1,8-octanediamine; N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]quinolin-4-amine trihydrochloride; N-4-Quinolyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane Hydrochloride Salt; N-4'-QUINOLYL-N'-9"-(1",2",3",4"-TETRAHYDRO-ACRIDINYL)-1,8-DIAMINOOCTANE DIHY
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H36N4
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| Canonical SMILES |
C1CCC2=NC3=CC=CC=C3C(=C2C1)NCCCCCCCCNC4=CC=NC5=CC=CC=C54
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| InChI |
1S/C30H36N4/c1(3-11-20-31-27-19-22-32-26-16-8-5-13-23(26)27)2-4-12-21-33-30-24-14-6-9-17-28(24)34-29-18-10-7-15-25(29)30/h5-6,8-9,13-14,16-17,19,22H,1-4,7,10-12,15,18,20-21H2,(H,31,32)(H,33,34)
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| InChIKey |
UNVOAAWEEGAXTN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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