Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01OUA
|
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| Former ID |
DIB005013
|
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| Drug Name |
TJN-598
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| Synonyms |
Glomerulonephritis therapy, Tsumura
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|
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| Indication | Glomerulonephritis [ICD-11: 5D00.Y] | Terminated | [1] | |
| Company |
Tsumura & Co
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 4A (PDE4A) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 4B (PDE4B) | Target Info | Inhibitor | [1] | |
| Phosphodiesterase 4D (PDE4D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Purine metabolism | |||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | DARPP-32 events | |||
| G alpha (s) signalling events | ||||
| WikiPathways | G Protein Signaling Pathways | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Opioid Signalling | ||||
| TSH signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of TJN-598, a new selective phosphodiesterase type IV inhibitor on anti-Thy1 nephritis in rats. Clin Exp Nephrol. 2011 Feb;15(1):14-24. | |||
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