Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01OZS
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| Former ID |
DNC011579
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| Drug Name |
3,3-Diisopropyl-dihydro-furan-2-one
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| Synonyms |
CHEMBL34879; 2(3H)-Furanone, dihydro-3,3-bis(1-methylethyl)-; SCHEMBL10358026; 132462-12-5
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H18O2
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| Canonical SMILES |
CC(C)C1(CCOC1=O)C(C)C
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| InChI |
1S/C10H18O2/c1-7(2)10(8(3)4)5-6-12-9(10)11/h7-8H,5-6H2,1-4H3
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| InChIKey |
HBNIKFYZKDWFNE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| Serotonergic synapse | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant ... J Med Chem. 1994 Jan 21;37(2):275-86. | |||
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