Drug Information
Drug General Information | Top | |||
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Drug ID |
D01PIU
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Former ID |
DNC004156
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Drug Name |
5-Chloro-3-ethyl-1-(4-fluoro-phenyl)-1H-indole
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Synonyms |
CHEMBL300907; 181116-12-1; 5-Chloro-3-ethyl-1-(4-fluoro-phenyl)-1H-indole; CTK0A6482; DTXSID30658199; BDBM50127987; ZINC13489982; AKOS030619591; 5-Chloro-3-ethyl-1-(4-fluorophenyl)-1H-indole; 1H-Indole, 5-chloro-3-ethyl-1-(4-fluorophenyl)-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H13ClFN
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Canonical SMILES |
CCC1=CN(C2=C1C=C(C=C2)Cl)C3=CC=C(C=C3)F
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InChI |
1S/C16H13ClFN/c1-2-11-10-19(14-6-4-13(18)5-7-14)16-8-3-12(17)9-15(11)16/h3-10H,2H2,1H3
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InChIKey |
APVXBLPJSJGGAJ-UHFFFAOYSA-N
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CAS Number |
CAS 181116-12-1
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Inhibitor | [1] |
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Voltage gated Potassium channels | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Hematopoietic Stem Cell Differentiation | ||||
Potassium Channels |
References | Top | |||
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REF 1 | Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches. Bioorg Med Chem Lett. 2003 May 19;13(10):1829-35. |
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