Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01PPZ
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| Former ID |
DNC012425
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| Drug Name |
Ridine-5-carboxylic acid ethyl ester
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| Synonyms |
ridine-5-carboxylic acid ethyl ester; CHEMBL87358; SCHEMBL10960643; 1-(3-Methylpentyl)-4-amino-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H24N4O2
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| Canonical SMILES |
CCC(C)CCN1C2=NC(=C(C(=C2C=N1)N)C(=O)OCC)C
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| InChI |
1S/C16H24N4O2/c1-5-10(3)7-8-20-15-12(9-18-20)14(17)13(11(4)19-15)16(21)22-6-2/h9-10H,5-8H2,1-4H3,(H2,17,19)
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| InChIKey |
YWSGZSUSPFMIIN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Serotonergic synapse | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents. J Med Chem. 1989 Dec;32(12):2561-73. | |||
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