Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01SEO
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| Former ID |
DIB012326
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| Drug Name |
ICI-181037
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| Synonyms |
ZM-181037
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Terminated | [1] | |
| Company |
Zeneca Group plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H34N2O4
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| Canonical SMILES |
CC(C(C1=CC=CC=C1OCC(=O)N)(C2=C(C=CC(=C2)C(C)(C)C)OC)O)N(C)C
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| InChI |
1S/C24H34N2O4/c1-16(26(5)6)24(28,18-10-8-9-11-21(18)30-15-22(25)27)19-14-17(23(2,3)4)12-13-20(19)29-7/h8-14,16,28H,15H2,1-7H3,(H2,25,27)/t16-,24-/m1/s1
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| InChIKey |
DLGGQRFVOGBFAX-VOIUYBSRSA-N
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| CAS Number |
CAS 138779-29-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001161) | |||
| REF 2 | ICI 181,037: a novel eukalemic diuretic with antiarrhythmic activity. Jpn J Pharmacol. 1991 Nov;57(3):263-77. | |||
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