Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01VIA
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| Former ID |
DNC010618
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| Drug Name |
(4-benzhydrylpiperazin-1-yl)(cyclohexyl)methanone
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| Synonyms |
CHEMBL1088730; AC1LKN75; (4-benzhydrylpiperazin-1-yl)(cyclohexyl)methanone; Oprea1_813517; Oprea1_627428; AC1Q5F91; MolPort-001-543-551; STK413456; BDBM50312578; ZINC19834645; AKOS003287837; MCULE-5141193554; ST50927985; 4-(diphenylmethyl)piperazinyl cyclohexyl ketone; (4-benzhydrylpiperazin-1-yl)-cyclohexylmethanone; 1-cyclohexanecarbonyl-4-(diphenylmethyl)piperazine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H30N2O
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| Canonical SMILES |
C1CCC(CC1)C(=O)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4
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| InChI |
1S/C24H30N2O/c27-24(22-14-8-3-9-15-22)26-18-16-25(17-19-26)23(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-2,4-7,10-13,22-23H,3,8-9,14-19H2
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| InChIKey |
OZIJATBNGVKZLU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Inhibitor | [1] |
| Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach. Eur J Med Chem. 2010 Mar;45(3):1133-9. | |||
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