Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01YIF
|
|||
| Former ID |
DIB020636
|
|||
| Drug Name |
PAC1
|
|||
| Synonyms |
PAC-1
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Anaplastic astrocytoma [ICD-11: 2A00.0; ICD-9: 191] | Phase 1 | [1], [2] | |
| Recurrent glioblastoma [ICD-11: 2A00.00; ICD-10: C71] | Phase 1 | [1], [2] | ||
| Structure |
 |
Download2D MOL |
||
| Formula |
C23H28N4O2
|
|||
| Canonical SMILES |
C=CCC1=C(C(=CC=C1)C=NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)O
|
|||
| InChI |
1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
|
|||
| InChIKey |
YQNRVGJCPCNMKT-LFVJCYFKSA-N
|
|||
| CAS Number |
CAS 315183-21-2
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 3 | Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2006 Oct;2(10):543-50. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.