Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02BGR
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| Former ID |
DIB018116
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| Drug Name |
(S)-N-[1-(3-morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide
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| Synonyms |
(S)-1 [PMID: 16904708]; compound 2 [PMID: 12852750]
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C21H24N2O2
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| Canonical SMILES |
CC(C1=CC(=CC=C1)N2CCOCC2)NC(=O)C=CC3=CC=CC=C3
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| InChI |
1S/C21H24N2O2/c1-17(22-21(24)11-10-18-6-3-2-4-7-18)19-8-5-9-20(16-19)23-12-14-25-15-13-23/h2-11,16-17H,12-15H2,1H3,(H,22,24)/b11-10+/t17-/m0/s1
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| InChIKey |
QMIMHUDEVKGOTQ-DVQDXYAYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv7.2 (KCNQ2) | Target Info | Activator | [1] |
| Voltage-gated potassium channel Kv7.4 (KCNQ4) | Target Info | Activator | [1] | |
| Voltage-gated potassium channel Kv7.5 (KCNQ5) | Target Info | Activator | [1] | |
| KEGG Pathway | Cholinergic synapse | |||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Reactome | Voltage gated Potassium channels | |||
| Interaction between L1 and Ankyrins | ||||
| WikiPathways | Potassium Channels | |||
| L1CAM interactions | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels. Neuropharmacology. 2006 Nov;51(6):1068-77. | |||
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