Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02EFK
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| Former ID |
DNC013204
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| Drug Name |
N1,2-dibenzyl-N3-hydroxy-N1-phenethylmalonamide
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| Synonyms |
CHEMBL426572
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C25H26N2O3
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| Canonical SMILES |
C1=CC=C(C=C1)CCN(CC2=CC=CC=C2)C(=O)C(CC3=CC=CC=C3)C(=O)NO
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| InChI |
1S/C25H26N2O3/c28-24(26-30)23(18-21-12-6-2-7-13-21)25(29)27(19-22-14-8-3-9-15-22)17-16-20-10-4-1-5-11-20/h1-15,23,30H,16-19H2,(H,26,28)
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| InChIKey |
PQZSZTWFWIQBGX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aminopeptidase N (ANPEP) | Target Info | Inhibitor | [1] |
| BioCyc | Glutathione-mediated detoxification | |||
| KEGG Pathway | Glutathione metabolism | |||
| Metabolic pathways | ||||
| Renin-angiotensin system | ||||
| Hematopoietic cell lineage | ||||
| Pathwhiz Pathway | Glutathione Metabolism | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
| Cardiac Progenitor Differentiation | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents. J Med Chem. 2007 Mar 22;50(6):1322-34. | |||
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