Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02EHL
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| Former ID |
DNC012287
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| Drug Name |
1-Benzo[b]thiophen-2-yl-cyclopentylamine
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| Synonyms |
CHEMBL18502; NCI60_038335; 1-Benzo[b]thiophen-2-yl-cyclopentylamine; AC1L9GGU; CTK7D5118; ZINC1657608; BDBM50040195; 1-(benzothiophen-2-yl)cyclopentan-1-amine; 1-(1-benzothiophen-2-yl)cyclopentan-1-amine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H15NS
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| Canonical SMILES |
C1CCC(C1)(C2=CC3=CC=CC=C3S2)N
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| InChI |
1S/C13H15NS/c14-13(7-3-4-8-13)12-9-10-5-1-2-6-11(10)15-12/h1-2,5-6,9H,3-4,7-8,14H2
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| InChIKey |
CHUXWBUYFQVPQD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine transporter (DAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Dopaminergic Neurogenesis | ||||
| Parkinsons Disease Pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| Neurotransmitter Clearance In The Synaptic Cleft | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-bin... J Med Chem. 1993 Apr 30;36(9):1188-93. | |||
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