Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02GNN
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| Former ID |
DNC010214
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| Drug Name |
N-methyl-3,3-diphenylpropan-1-amine
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| Synonyms |
N-Methyl-3,3-diphenylpropylamine; 28075-29-8; N-methyl-3,3-diphenylpropan-1-amine; W-107076; EINECS 248-821-5; n-methyl-3,3-diphenylpropan-1-amin; Diphenylpropyl-methylamin; AC1L3PJ5; AC1Q1HZ6; diphenylalkylamine (DPA), 5b; CHEMBL593494; SCHEMBL3638413; Jsp005413; Methyl(3,3-diphenylpropyl)amine; BDBM35933; CTK4G0777; (3,3-Diphenylpropyl)methylamine; DTXSID00182350; AKEGHAUFMKCWGX-UHFFFAOYSA-N; 3,3-Diphenyl-N-methylpropylamine; MolPort-003-737-089; ZINC5996308; ACT07251; Benzenepropanamine,N-methyl-g-phenyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H19N
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| Canonical SMILES |
CNCCC(C1=CC=CC=C1)C2=CC=CC=C2
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| InChI |
1S/C16H19N/c1-17-13-12-16(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3
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| InChIKey |
AKEGHAUFMKCWGX-UHFFFAOYSA-N
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| CAS Number |
CAS 28075-29-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| Histamine H1 receptor (H1R) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Histamine H1 receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| Histamine receptors | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| IL-4 Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. Bioorg Med Chem. 2009 Sep 15;17(18):6496-504. | |||
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