Drug Information
Drug General Information | Top | |||
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Drug ID |
D02HZG
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Former ID |
DNC010460
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Drug Name |
2-(2-Bromophenoxy)-N,N-dimethylethanamine
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Synonyms |
886851-37-2; 2-(2-Dimethylaminoethoxy)-bromobenzene; 2-(2-Bromophenoxy)-N,N-dimethylethanamine; CHEMBL599818; [2-(2-bromophenoxy)ethyl]dimethylamine; AC1LHJHJ; SCHEMBL1857526; DTXSID50358341; MolPort-004-331-572; ZINC4914895; KS-000000PE; BDBM50307492; 2-(2-dimethylaminoethoxy)bromobenzene; AKOS000170274; MCULE-8721188188; AM87375; AS-44355; AJ-52607; KB-323008; Y-0778
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H14BrNO
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Canonical SMILES |
CN(C)CCOC1=CC=CC=C1Br
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InChI |
1S/C10H14BrNO/c1-12(2)7-8-13-10-6-4-3-5-9(10)11/h3-6H,7-8H2,1-2H3
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InChIKey |
OUWAXRLVNYTZJK-UHFFFAOYSA-N
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CAS Number |
CAS 886851-37-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 7 receptor (HTR7) | Target Info | Inhibitor | [1] |
KEGG Pathway | Ras signaling pathway | |||
Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling. Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. |
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