Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02IIW
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| Former ID |
DAP001477
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| Drug Name |
Faropenem
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| Synonyms |
FPM; Fropenem; (+)-(5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-((2R)-tetrahydro-2-furyl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid; (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 6alpha-[(1R)-1-hydroxyethyl]-2-[(2R)-tetrahydrofuran-2-yl]-2,3-didehydropenam-3-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Gram-positive bacterial infection [ICD-11: 1B74-1G40] | Approved | [1] | |
| Therapeutic Class |
Respiratory Agents
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| Company |
Suntory
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| Structure |
 |
Download2D MOL |
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| Formula |
C12H15NO5S
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| Canonical SMILES |
CC(C1C2N(C1=O)C(=C(S2)C3CCCO3)C(=O)O)O
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| InChI |
1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1
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| InChIKey |
HGGAKXAHAYOLDJ-FHZUQPTBSA-N
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| CAS Number |
CAS 106560-14-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8190018, 14751073, 14873173, 43122633, 46488294, 49830260, 57269840, 57315812, 76220957, 85174229, 103692894, 104334952, 124766192, 124893155, 126682935, 128056539, 131293830, 135024186, 137022387, 137337538, 144205728, 152034491, 152164570, 162475718, 164814834, 170466271, 180100885, 198979214, 206246326, 223434991, 223653966, 223656600, 223710364, 226590130, 251912321, 251916636, 252358704
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| ChEBI ID |
CHEBI:51257
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Dihydropteroate synthetase (Bact folP) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for bacterial urinary tract infections. Expert Opin Emerg Drugs. 2005 May;10(2):275-98. | |||
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