Drug Information
Drug General Information | Top | |||
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Drug ID |
D02IKF
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Drug Name |
M9831
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Synonyms |
2-Methyl-1,3-benzothiazole-5-carboxylic acid; 24851-69-2; 2-Methylbenzo[d]thiazole-5-carboxylic acid; 2-Methyl-benzothiazole-5-carboxylic acid; 2-methyl-1,3-benzothiazole-5-carboxylic acid; 5-Benzothiazolecarboxylic acid, 2-methyl-; 2-methylbenzothiazole-5-carboxylic acid; SMR000015267; MLS000030206; AC1LDLFR; AC1Q2PD7; SCHEMBL1105986; cid_649953; CHEMBL1480093; CTK0J4554; KS-00000IVD; BDBM87603; DTXSID50349491; MolPort-002-499-021; TVUFPZOJUJGDDD-UHFFFAOYSA-N; HMS2396B08; ZINC873707; ZX-CM001754; ZX-AL001070; ANW-56675; AKOS000320290; FCH1781098; CS-W019372; MCULE-8154234969; FS
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1] | |
Company |
EMD Serono Rockland, MA
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Structure |
Download2D MOL |
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Formula |
C9H7NO2S
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Canonical SMILES |
CC1=NC2=C(S1)C=CC(=C2)C(=O)O
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InChI |
1S/C9H7NO2S/c1-5-10-7-4-6(9(11)12)2-3-8(7)13-5/h2-4H,1H3,(H,11,12)
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InChIKey |
TVUFPZOJUJGDDD-UHFFFAOYSA-N
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CAS Number |
CAS 24851-69-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | DNA-dependent protein kinase catalytic (PRKDC) | Target Info | Inhibitor | [1] |
KEGG Pathway | Non-homologous end-joining | |||
Cell cycle | ||||
NetPath Pathway | IL1 Signaling Pathway | |||
Pathway Interaction Database | DNA-PK pathway in nonhomologous end joining | |||
Coregulation of Androgen receptor activity | ||||
Class I PI3K signaling events mediated by Akt | ||||
BARD1 signaling events | ||||
Reactome | Nonhomologous End-Joining (NHEJ) | |||
WikiPathways | DNA Damage Response | |||
Non-homologous end joining | ||||
FAS pathway and Stress induction of HSP regulation | ||||
Cytosolic sensors of pathogen-associated DNA | ||||
Retinoblastoma (RB) in Cancer | ||||
Prostate Cancer | ||||
Double-Strand Break Repair | ||||
Cell Cycle | ||||
miRNA Regulation of DNA Damage Response |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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