Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02JOZ
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| Former ID |
DNC011401
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| Drug Name |
4-Bromo-6-nitro-2-piperazin-1-yl-quinoline
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| Synonyms |
4-Bromo-6-nitroquipazine; 143954-73-8; CHEMBL167825; 4-Bromo-6-nitro-2-piperazin-1-yl-quinoline; Quinoline, 4-bromo-6-nitro-2-(1-piperazinyl)-; ACMC-20n3fo; SCHEMBL6364738; AC1L318Y; CTK0I3188; DTXSID50162581; NRCNLRMWSMFETI-UHFFFAOYSA-N; BDBM50110574
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H13BrN4O2
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| Canonical SMILES |
C1CN(CCN1)C2=NC3=C(C=C(C=C3)[N+](=O)[O-])C(=C2)Br
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| InChI |
1S/C13H13BrN4O2/c14-11-8-13(17-5-3-15-4-6-17)16-12-2-1-9(18(19)20)7-10(11)12/h1-2,7-8,15H,3-6H2
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| InChIKey |
NRCNLRMWSMFETI-UHFFFAOYSA-N
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| CAS Number |
CAS 143954-73-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serotonin transporter (SERT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
| 5HT2 type receptor mediated signaling pathway | ||||
| 5HT3 type receptor mediated signaling pathway | ||||
| 5HT4 type receptor mediated signaling pathway | ||||
| WikiPathways | Monoamine Transport | |||
| SIDS Susceptibility Pathways | ||||
| NRF2 pathway | ||||
| Synaptic Vesicle Pathway | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-substituted 6-nitroquipazines. Bioorg Med Chem Lett. 2002 Mar 11;12(5):811-5. | |||
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