Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02KAF
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| Former ID |
DIB011815
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| Drug Name |
GT-2203
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| Synonyms |
GT-2144; GT-2204; GT-2223; GT-2328; GT-2396; GT-2397; GT-2431; H3 agonists, Gliatech
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Terminated | [1] | |
| Company |
Gliatech Inc
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| Structure |
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Download2D MOL |
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| Formula |
C6H9N3
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| Canonical SMILES |
C1C(C1N)C2=CN=CN2
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| InChI |
1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5-/m1/s1
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| InChIKey |
OWWNABDDYQLERE-RFZPGFLSSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008938) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | |||
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