Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02KLW
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| Former ID |
DNC005812
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| Drug Name |
DIZOCILPINE
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| Synonyms |
DIZOCILPINE; 77086-21-6; MK-801 (Dizocilpine); UNII-7PY8KH681I; MK-801; Lopac-M-108; Lopac-M-107; MK 801; Prestwick0_000109; (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene; 7PY8KH681I; CHEMBL284237; CHEBI:34725; Dizocilpine [INN]; Dizocilpinum [INN-Latin]; Dizocilpina [INN-Spanish]; Dizocilpinum; Dizocilpina; MK801; MK-801(Dizocilpine); HSDB 7641; (+)MK-801; (+)-MK-801; (+/-)-MK801; Prestwick2_000109; Prestwick3_000109; Prestwick1_000109; Biomol-NT_000210; SCHEMBL34528; Lopac0_000872; BSPBio_000098; SPBio_002037
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| Drug Type |
Small molecular drug
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H15N
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| Canonical SMILES |
CC12C3=CC=CC=C3CC(N1)C4=CC=CC=C24
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| InChI |
1S/C16H15N/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16/h2-9,15,17H,10H2,1H3/t15-,16+/m1/s1
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| InChIKey |
LBOJYSIDWZQNJS-CVEARBPZSA-N
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| CAS Number |
CAS 77086-21-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
586326, 603151, 7979108, 10259226, 11111403, 11111404, 11466137, 11467257, 11485773, 16107416, 16180231, 26751971, 33503095, 47216999, 47217000, 47291334, 47291335, 47440489, 47736714, 47885615, 47959980, 47959981, 48259469, 48334731, 49698349, 50104646, 57395705, 77234575, 85787792, 85787950, 90341814, 103193630, 103939283, 104431219, 124750063, 124882687, 124882688, 131347199, 134343017, 135650617, 136080151, 137100768, 162009802, 162022805, 179151131, 198949394, 223366874, 223442356, 225082654, 226087978
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| ChEBI ID |
CHEBI:34725
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2403). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000713) | |||
| REF 3 | 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacolog... J Med Chem. 2005 Nov 3;48(22):6887-96. | |||
| REF 4 | Synthesis and evaluation of 6,11-ethanohexahydrobenzo[b]quinolizidines: a new class of noncompetitive N-methyl-D-aspartate antagonists. J Med Chem. 1995 Jun 23;38(13):2483-9. | |||
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