Drug Information
Drug General Information | Top | |||
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Drug ID |
D02KRI
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Former ID |
DIB010205
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Drug Name |
Epristeride
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Synonyms |
Zariflo; ONO-9302; SKB-105657; SKF-105657
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Drug Type |
Small molecular drug
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Indication | Hirsutism [ICD-11: ED72; ICD-10: L68.0; ICD-9: 704.1] | Phase 3 | [1] | |
Company |
SmithKline Beecham plc
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Structure |
Download2D MOL |
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Formula |
C25H37NO3
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Canonical SMILES |
CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CC=C4C3(CCC(=C4)C(=O)O)C
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InChI |
1S/C25H37NO3/c1-23(2,3)26-21(27)20-9-8-18-17-7-6-16-14-15(22(28)29)10-12-24(16,4)19(17)11-13-25(18,20)5/h6,14,17-20H,7-13H2,1-5H3,(H,26,27)(H,28,29)/t17-,18-,19-,20+,24-,25-/m0/s1
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InChIKey |
VAPSMQAHNAZRKC-PQWRYPMOSA-N
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CAS Number |
CAS 119169-78-7
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:31552
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Target and Pathway | Top | |||
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Target(s) | Oxo-5-alpha-steroid 4-dehydrogenase (SRD5A) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Epristeride SmithKline Beecham. IDrugs. 1998 May;1(1):152-7. | |||
REF 2 | Discovery of a novel hybrid from finasteride and epristeride as 5alpha-reductase inhibitor. Bioorg Med Chem Lett. 2011 Jan 1;21(1):475-8. |
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