Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02NKD
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| Former ID |
DNC012499
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| Drug Name |
8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine
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| Synonyms |
CHEMBL161465; 6-Phenyl-8-(3-nitrophenyl)-1,7-naphthyridine; 8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine; SCHEMBL7015917; SRVUGPYWYLBZNI-UHFFFAOYSA-N; ZINC13805266
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H13N3O2
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NC(=C3C(=C2)C=CC=N3)C4=CC(=CC=C4)[N+](=O)[O-]
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| InChI |
1S/C20H13N3O2/c24-23(25)17-10-4-8-15(12-17)20-19-16(9-5-11-21-19)13-18(22-20)14-6-2-1-3-7-14/h1-13H
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| InChIKey |
SRVUGPYWYLBZNI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 4A (PDE4A) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 4B (PDE4B) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Purine metabolism | |||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | DARPP-32 events | |||
| G alpha (s) signalling events | ||||
| WikiPathways | G Protein Signaling Pathways | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Palladium-catalyzed cross-coupling reactions for the synthesis of 6, 8-disubstituted 1,7-naphthyridines: a novel class of potent and selective phos... J Med Chem. 2000 Feb 24;43(4):675-82. | |||
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