Drug Information
Drug General Information | Top | |||
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Drug ID |
D02NNZ
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Drug Name |
1,2,4-triazole derivative 1
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Synonyms |
PMID26161824-Compound-92
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Drug Type |
Small molecular drug
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Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Patented | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H16Cl3N5O
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Canonical SMILES |
C1CCN(C1)NC(=O)C2=NN(C(=N2)C3=CC=C(C=C3)Cl)C4=C(C=C(C=C4)Cl)Cl
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InChI |
1S/C19H16Cl3N5O/c20-13-5-3-12(4-6-13)18-23-17(19(28)25-26-9-1-2-10-26)24-27(18)16-8-7-14(21)11-15(16)22/h3-8,11H,1-2,9-10H2,(H,25,28)
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InChIKey |
ONYKENLNZNVNBN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Antagonist | [1] |
Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Retrograde endocannabinoid signaling | ||||
Panther Pathway | Endogenous cannabinoid signaling | |||
Pathway Interaction Database | N-cadherin signaling events | |||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Small Ligand GPCRs | ||||
BDNF signaling pathway | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116. |
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