Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02TKI
|
|||
| Former ID |
DNC004178
|
|||
| Drug Name |
L-733060
|
|||
| Synonyms |
L-733060; L 733060; 148700-85-0; L-733,060 hydrochloride; L-733061; L 733061; L 733,061; L 733,060; L-733,061; CHEMBL27006; 3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine; L-733,060; (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine; Tocris-1145; AC1L31OI; Lopac0_000752; SCHEMBL1282817; CHEBI:92286; FCDRFVCGMLUYPG-ROUUACIJSA-N; ZINC3809445; BDBM50049468; AKOS030230939; CCG-204837; API0013970; NCGC00025030-02; NCGC00025030-01; KB-78050; l733060; LS-114326; BRD-K15791587-003-01-7
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H19F6NO
|
|||
| Canonical SMILES |
C1CC(C(NC1)C2=CC=CC=C2)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
|
|||
| InChI |
1S/C20H19F6NO/c21-19(22,23)15-9-13(10-16(11-15)20(24,25)26)12-28-17-7-4-8-27-18(17)14-5-2-1-3-6-14/h1-3,5-6,9-11,17-18,27H,4,7-8,12H2/t17-,18-/m0/s1
|
|||
| InChIKey |
FCDRFVCGMLUYPG-ROUUACIJSA-N
|
|||
| CAS Number |
CAS 148700-85-0
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:92286
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Substance-P receptor (TACR1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3-Benzyloxy-2-phenylpiperidine NK1 antagonists: the influence of alpha methyl substitution, Bioorg. Med. Chem. Lett. 7(23):2959-2962 (1997). | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.